{"id":1784,"date":"2024-04-11T17:08:06","date_gmt":"2024-04-11T08:08:06","guid":{"rendered":"https:\/\/www.jpscs.org\/?p=1784"},"modified":"2024-04-11T17:08:06","modified_gmt":"2024-04-11T08:08:06","slug":"%e6%9c%89%e5%ae%b3%e5%8f%8d%e5%bf%9c","status":"publish","type":"post","link":"https:\/\/www.jpscs.org\/?p=1784","title":{"rendered":"\u6709\u5bb3\u53cd\u5fdc"},"content":{"rendered":"\n

\u3086\u3046\u304c\u3044\u306f\u3093\u306e\u3046<\/p>\n\n\n\n

Adverse reaction<\/p>\n\n\n\n

\u5b9a\u7fa9
(1) \u6b63\u3057\u3044\u30d7\u30ed\u30bb\u30b9\u306b\u5f93\u3063\u3066\u9069\u5207\u306a\u884c\u52d5\u306b\u3088\u3063\u3066\u5b9f\u65bd\u3055\u308c\u305f\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u60a3\u8005\u306b\u767a\u751f\u3057\u305f\u4e88\u671f\u305b\u306c\u5bb3
(WHO, 2020)\uff0e
(2) \uff08\u5e02\u8ca9\u5f8c\u306e\uff09\u533b\u85ac\u54c1\u306b\u3088\u308b\u53cd\u5fdc\u306e\u4e2d\u3067\uff0c\u901a\u5e38\u7528\u3044\u3089\u308c\u308b\u7528\u91cf\u3067\u8d77\u3053\u308b\u597d\u307e\u3057\u304f\u306a\u3044\u53cd\u5fdc 1,2)<\/sup>
(3) \u81e8\u5e8a\u4f7f\u7528\u306e\u627f\u8a8d\u524d\u306e\u65b0\u898f\u533b\u85ac\u54c1\u306e\u4f7f\u7528\u4e2d\u306b\u767a\u751f\u3057\u305f\uff0c\u533b\u85ac\u54c1\u306e\u4f7f\u7528\u3068\u95a2\u9023\u3057\u3066\u751f\u3058\u305f\u3042\u3089\u3086\u308b\u6709\u5bb3
\u4e8b\u8c61\u3084\u4e88\u671f\u3057\u306a\u3044\u53cd\u5fdc(adverse drug reaction) 2)<\/sup>\uff0e\u65e5\u672c\u8a9e\u3067\u306f\u526f\u4f5c\u7528\u3068\u3044\u3046\u7528\u8a9e\u306b\u8a33\u3055\u308c\u3066\u3044\u308b
\u89e3\u8aac
(1) \u6709\u5bb3\u4e8b\u8c61\u306e\u8aac\u660e\u3067\u8ff0\u3079\u305f\u3088\u3046\u306b\uff0cadverse event \u306f\u56de\u907f\u53ef\u80fd\u306a\u3067\u304d\u3054\u3068\u3068\u5b9a\u7fa9\u3057\uff0c\u305d\u308c\u306b\u5bfe\u3057\u3066\uff0c
adverse reaction \u306f\uff0cnon-preventable\uff08\u56de\u907f\u4e0d\u53ef\u80fd\u306a\uff09\u3067\u304d\u3054\u3068\u3068\u5b9a\u7fa9\u3059\u308b\u8003\u3048\u65b9\u304c\u3042\u308b\uff0e\u4f8b\u3048\u3070\uff0c\u8853
\u5f8c\u306e\u9759\u8108\u8840\u6813\u585e\u6813\u75c7\u3092\u4e88\u9632\u3059\u308b\u305f\u3081\u306e\u6a19\u6e96\u7684\u4e88\u9632\u7b56\u3092\u8b1b\u3058\u3066\u3044\u305f\u306b\u3082\u95a2\u308f\u3089\u305a\uff0c\u81f4\u6b7b\u7684\u306a\u80ba\u8840\u6813\u75c7\u3092\u767a
\u75c7\u3057\u305f\u5834\u5408\u306b\u306f\uff0c\u6709\u5bb3\u53cd\u5fdc\u3068\u3057\u3066\uff0c\u56de\u907f\u4e0d\u53ef\u80fd\u3067\u3042\u3063\u305f\u3068\u4f4d\u7f6e\u4ed8\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u308b\uff0e\u3057\u304b\u3057\uff0c\u3053\u306e\u3088\u3046
\u306a\u4e8b\u4f8b\u3082\u5b66\u7fd2\u306e\u5bfe\u8c61\u3067\u3042\u308b\u3068\u6349\u3048\uff0c\u3088\u308a\u3088\u3044\u518d\u767a\u9632\u6b62\u7b56\u3092\u691c\u8a0e\u3057\uff0c\u4e88\u9632\u7b56\u3092\u6539\u8a02\u3059\u308b\u3068\u3044\u3046\u3053\u3068\u3082\u3067\u304d
\u308b\uff0e\u305f\u3060\u3057\uff0c\u5bfe\u7b56\u3092\u5909\u66f4\u3057\u3066\u3082\uff0c\u6709\u5bb3\u4e8b\u8c61\u3092\u30bc\u30ed\u306b\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u305a\uff0c\u307e\u305f\uff0c\u65b0\u305f\u306a\u5bfe\u7b56\u304c\u5225\u306e\u30ea\u30b9\u30af
\u3092\u751f\u3080\u5834\u5408\u3082\u3042\u308b\uff0e\u3053\u306e\u3088\u3046\u306b\u3069\u306e\u7acb\u5834\u3092\u3068\u308b\u304b\u3068\u3044\u3046\u9055\u3044\u306b\u3088\u3063\u3066\uff0c\u56de\u907f\u53ef\u80fd\u3067\u3042\u3063\u305f\u304b\u4e0d\u53ef\u80fd\u3067\u3042
\u3063\u305f\u304b\u3068\u3044\u3046\u5224\u65ad\u3082\u7570\u306a\u308b\u3068\u601d\u308f\u308c\u308b\uff0e
(2) \u533b\u85ac\u54c1\u3092\u6dfb\u4ed8\u6587\u66f8\u306e\u901a\u308a\u306b\u4f7f\u7528\u3057\u305f\u3068\u3057\u3066\u3082\u526f\u4f5c\u7528\u304c\u751f\u3058\u308b\u3053\u3068\u304c\u3042\u308a\uff0c\u3053\u308c\u3092\u6709\u5bb3\u53cd\u5fdc\u3068\u3044\u3046\uff0e
\u3053\u306e\u8003\u3048\u306f\uff0c(1)\u306e\u6709\u5bb3\u306a\u30a4\u30f3\u30b7\u30c7\u30f3\u30c8\u3092\u6709\u5bb3\u4e8b\u8c61\u3068\u6709\u5bb3\u53cd\u5fdc\u306b\u533a\u5225\u3059\u308b\u8003\u3048\u65b9\u306b\u3082\u901a\u3058\u308b\uff0e\u4e00\u65b9\u3067\uff0c\u627f
\u8a8d\u524d\u306e\u533b\u85ac\u54c1\u306b\u3064\u3044\u3066\u306f\uff0c\u3069\u306e\u3088\u3046\u306a\u6709\u5bb3\u4e8b\u8c61\u304c\u767a\u751f\u3059\u308b\u304b\u308f\u304b\u3063\u3066\u3044\u306a\u3044\u305f\u3081\u306b\uff0c\u6295\u4e0e\u5f8c\u306b\u751f\u3058\u305f\u3042
\u3089\u3086\u308b\u6709\u5bb3\u4e8b\u8c61\u3092\u53ce\u96c6\u3059\u308b\uff0e\u5f8c\u306b\uff0c\u56e0\u679c\u95a2\u4fc2\u306e\u6709\u7121\u304c\u5224\u660e\u3059\u308b\u304b\u3082\u3057\u308c\u306a\u3044\u304c\uff0c\u305d\u306e\u6642\u70b9\u3067\u306f\uff0c\u533b\u85ac\u54c1
\u3068\u306e\u95a2\u9023\u306f\u4e0d\u660e\u3067\u3042\u308b\u305f\u3081\u3067\u3042\u308b\uff0e\u3053\u308c\u3082\u6709\u5bb3\u306a\u30a4\u30f3\u30b7\u30c7\u30f3\u30c8\u306e\u8003\u3048\u306b\u901a\u3058\u308b\u90e8\u5206\u304c\u3042\u308a\uff0c\u5168\u3066\u306e\u6709\u5bb3
\u306a\u30a4\u30f3\u30b7\u30c7\u30f3\u30c8\u306f\uff0c\u56de\u907f\u53ef\u80fd\u304b\u3069\u3046\u304b\u306f\u767a\u751f\u6642\u306b\u306f\u4e0d\u660e\u306a\u305f\u3081\uff0c\u5831\u56fd\u5bfa\u306b\u306f\u6709\u5bb3\u53cd\u5fdc\u3068\u3057\u3066\u533a\u5225\u305b\u305a\u306b
\u5168\u3066\u6709\u5bb3\u4e8b\u8c61\u3068\u3057\u3066\u304a\u304f\u3068\u3044\u3046\u8003\u3048\u3082\u5408\u7406\u7684\u3067\u3042\u308b\uff0e
\u53c2\u8003\u6587\u732e
1) \u65e5\u672c\u85ac\u5b66\u4f1a\uff0e\u85ac\u5b66\u7528\u8a9e\u89e3\u8aac\uff0e
https:\/\/www.pharm.or.jp\/dictionary\/wiki.cgi?%E5%89%AF%E4%BD%9C%E7%94%A8<\/a>
2) Guideline for good clinical practice E6(R2). (2016) [\u30a2\u30af\u30bb\u30b9\u65e5 2023.05.07]
https:\/\/www.ema.europa.eu\/en\/documents\/scientific-guideline\/ich-guideline-good-clinicalpractice-e6r2-step-5_en.pdf<\/a>[\u30a2\u30af\u30bb\u30b9\u65e5 2023.05.07<\/p>\n\n\n\n

\u672c\u7528\u8a9e\u306b\u5bfe\u3059\u308b\u3054\u610f\u898b\u304c\u3054\u3056\u3044\u307e\u3057\u305f\u3089\u3001\u3053\u3061\u3089\u304b\u3089\u304a\u5bc4\u305b\u304f\u3060\u3055\u3044\u3002<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

\u3086\u3046\u304c\u3044\u306f\u3093\u306e\u3046 Adverse reaction \u5b9a\u7fa9(1) \u6b63\u3057\u3044\u30d7\u30ed\u30bb\u30b9\u306b\u5f93\u3063\u3066\u9069\u5207\u306a\u884c\u52d5\u306b\u3088\u3063\u3066\u5b9f\u65bd\u3055\u308c\u305f\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u60a3\u8005\u306b\u767a\u751f\u3057\u305f\u4e88\u671f\u305b\u306c\u5bb3(WHO, 2020)\uff0e(2) \uff08\u5e02\u8ca9\u5f8c\u306e\uff09\u533b\u85ac\u54c1\u306b\u3088\u308b\u53cd\u5fdc\u306e\u4e2d\u3067\uff0c […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-1784","post","type-post","status-publish","format-standard","hentry","category-7"],"_links":{"self":[{"href":"https:\/\/www.jpscs.org\/index.php?rest_route=\/wp\/v2\/posts\/1784","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.jpscs.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.jpscs.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.jpscs.org\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.jpscs.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1784"}],"version-history":[{"count":2,"href":"https:\/\/www.jpscs.org\/index.php?rest_route=\/wp\/v2\/posts\/1784\/revisions"}],"predecessor-version":[{"id":1826,"href":"https:\/\/www.jpscs.org\/index.php?rest_route=\/wp\/v2\/posts\/1784\/revisions\/1826"}],"wp:attachment":[{"href":"https:\/\/www.jpscs.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1784"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.jpscs.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1784"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.jpscs.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1784"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}